Louisiana has a cost of living index of 91 relative to the US average of 100. This is close to the national average. Louisiana offers a typical cost structure — housing and expenses track closely to US median.
The 4% safe withdrawal rule suggests a FIRE number of 25x annual expenses. At Louisiana's median income of $52,800, that is $1,320,000. However, if you plan to spend more (or less) than median income in retirement, scale the number accordingly.
Louisiana taxes income at 1.85%–4.25%. In FIRE, your primary income comes from portfolio withdrawals, dividends, and capital gains. Long-term capital gains in LA are taxed at the same rate as ordinary income, including IRA withdrawals. Factor this into your withdrawal rate planning.